Detailed Information for N00166
IPAD-DB ID N00166
Name Phytol-PLGA NPs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ25-35
Effects (1) Decreased Aβ deposition & ROS ,(2) downregulated the expression of AD associated genes viz Aβ, ace-1 and hsp-4
Research Models Neuro-2a cells (mouse neuroblastoma cell line)
Main Source
Ref. Link