Detailed Information for N00170
IPAD-DB ID N00170
Name γ-secretase inhibitors (GSIs)
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ40
Effects (1) GSIs inhibit production of all Aβ species;(2) GSMs reduce Aβ42 and Aβ41 and increase the levels of smaller Aβ species
Research Models Mouse IgGs against Tau
Main Source
Ref. Link