Detailed Information for N00173
IPAD-DB ID N00173
Name MSN-BBR-L lipid
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Aβ40
Effects (1) BBR-mediated neuroprotection is related to the inhibition of the Akt/ERK1/2 survival/apoptotic signaling pathway/GSK3β/caspase-3 activity and the Jun aminoterminal kinase (JNK) pathway.
Research Models Swiss albino male mice (25 ± 5 g)
Main Source
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