Detailed Information for N00175
IPAD-DB ID N00175
Name  -CQ-PBCA NPs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating DTPA,CQ
BBB(blood-brain barrier) PASS
Target Protein Aβ1-42
Effects (1) It polymerized with the most reproducibility; it crossed the BBB and had a rapid uptake and clearance from the normal brain.(2) the lipophilicity of the carrier
Research Models Mice with a double mutation (APP/PS1)
Main Source
Ref. Link