Detailed Information for N00188
IPAD-DB ID N00188
Name nanoparticles (SLNs-CUR)
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Aβ
Effects (1) Differently modulate TG2 isoforms acting on apoptotic pathway activation or on the ability of the protein to repair cellular damage in the brains of Tg mice(2) reduce TG2-S expression,increase TG2-L levels
Research Models Wild Type (WT) and in TgCRND8 (Tg) mice\two mutated human amyloid precursor protein (APP) genes
Main Source
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