Detailed Information for N00198
IPAD-DB ID N00198
Name Chondroitin sulphate nano-selenium (CS@Se)
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Glycogen synthase kinase-3 beta (GSK-3β)
Effects CS@Se can reduce oxidative stress damage, inhibit excessive tau phosphorylation, reduce inflammation to delay AD development, and increase the learning and memory capacities of AD mice.
Research Models A mouse model of Alzheimer's disease
Main Source
Ref. Link