IPAD-DB ID |
N00198 |
Name |
Chondroitin sulphate nano-selenium (CS@Se) |
Category |
Nano-inhibitors |
EC50 |
|
IC50 |
|
Inhibition |
|
Toxicity |
|
ROS(reactive oxygen species) |
|
Metal Chelating |
|
BBB(blood-brain barrier) |
|
Target Protein |
Glycogen synthase kinase-3 beta (GSK-3β) |
Effects |
CS@Se can reduce oxidative stress damage, inhibit excessive tau phosphorylation, reduce inflammation to delay AD development, and increase the learning and memory capacities of AD mice. |
Research Models |
A mouse model of Alzheimer's disease |
Main Source |
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Ref. Link |
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