Detailed Information for N00199
IPAD-DB ID N00199
Name Ag-nano particles (Ag-NPs)
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity No.
ROS(reactive oxygen species)
Metal Chelating Ag
BBB(blood-brain barrier)
Target Protein Hen egg white lysozyme (HEWL)
Effects (1) Ag-NPs increased the percentage of time elapsed and the distance swum in the target quadrant in the rat model of AD. (2) Ag-NPs improved spatial learning and memory by inhibiting amyloid fibril-induced neurotoxicity.
Research Models The rat model of AD
Main Source
Ref. Link