Detailed Information for N00200
IPAD-DB ID N00200
Name ZnONP ST
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein HEWL amyloid
Effects (1) ZnONP demonstrated a dose-dependent inhibition of fibrillar amyloid growth of HEWL, with the greatest effect being exhibited by ZnONPST.(2) ZnONPST prolonged the nucleation phase and shortened the elongation phase of HEWL amyloid growth
Research Models Mice neuroblastoma cell line, N2a and human keratinocyte cell line
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