Detailed Information for N00203
IPAD-DB ID N00203
Name the heparin-protamine sulfate-ferumoxytol nanocomplex
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs)
Effects (1) Observed in vitro ferumoxytol labeling of hUCB-MSCs in both adhered and detached states. Iron-positive staining of detached ferumoxytol-labeled hUCB-MSCs confirmed the stability of ferumoxytol labeling even after multiple washings, centrifugation, and re-suspension(2) iron-positive hUCB-MSCs were accurately delivered and engrafted into the mouse hippocampus.(3)
Research Models 5XFAD transgenic AD mice
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