the heparin-protamine sulfate-ferumoxytol nanocomplex
Category
Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein
Human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs)
Effects
(1) Observed in vitro ferumoxytol labeling of hUCB-MSCs in both adhered and detached states. Iron-positive staining of detached ferumoxytol-labeled hUCB-MSCs confirmed the stability of ferumoxytol labeling even after multiple washings, centrifugation, and re-suspension(2) iron-positive hUCB-MSCs were accurately delivered and engrafted into the mouse hippocampus.(3)
