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Detailed Information for N00207
IPAD-DB ID
N00207
Name
NGF-SPIO-Au NPs
Category
Nano-inhibitors
EC
50
IC
50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein
Integrin-β1
Effects
DMF stimulation of NGF-SPIO-Au NPs resulted in a significant upregulation of integrin-β1 expression compared to NGF-SPIO-Au NPs alone (P < 0.05) , while there was no significant difference in integrin-β1 expression between SMF and DMF stimulation
Research Models
PC-12 cells (from rat pheochromocytoma)
Main Source
Ref. Link