Detailed Information for N00214
IPAD-DB ID N00214
Name sensitive nanoparticles composed of succinyl β-cyclodextrin (bCDsu)
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein NMDAR1 protein
Effects (1) BCDsuMema nanoparticles have the capacity to suppress NMDAR1 expression in brain cells, which has relevance to applications in Alzheimer’s disease
Research Models SH-SY5Y Neuroblastoma Cells,U87MG glioblastoma cells
Main Source
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