Detailed Information for N00225
IPAD-DB ID N00225
Name HMPWCs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species) scavenge ROS
Metal Chelating
BBB(blood-brain barrier)
Target Protein Tau protein
Effects Suppress the activation of microglia and astrocytes to regulate neuroinflammation, and eliminate the phosphorylation and aggregation of Tau via the AKT/GSK-3β pathway；attenuate the cognitive impairments of Tau-related AD-like rats
Research Models SH-SY5Y cells；SD rats
Main Source
Ref. Link