(1) SERS and TERS spectra confirm the changed conformation of α-Syn after incubation for 24 h at 37 °C. The SERS spectrum is richer than the TERS spectrum(2) the interaction of α-synuclein with the surface of nanoparticles at such concentrations has a moderate affinity, at 4 °C and 37 °C show that α-synuclein aggregation intensifies with increasing temperature
Research Models
The interactions between TiO2-NPs and ZnO-NPs on the aggregation kinetics of β amyloid fragment 1-40 and α-synuclein protein were investigated by surface-enhanced Raman spectroscopy (SERS) and tip-enhanced Raman spectroscopy (TERS)
