Detailed Information for N00241
IPAD-DB ID N00241
Name functionalized gold nanorods (GNRs-PEG-D1)
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating Au
BBB(blood-brain barrier)
Target Protein Aβ
Effects (1) CRANAD-2 allows the detection of insoluble Aβ species (ag_x0002_gregates/fibrils) in the C. elegans model. (2) CRANAD-58 preferentially detects soluble Aβ species in the C. elegans model. (3) GNRs increase CRANAD fluorescence associated with Aβ in vitro.
Research Models AD mouse models, C. elegans
Main Source
Ref. Link