Detailed Information for N00244
IPAD-DB ID N00244
Name IN-NLC
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ
Effects Improve the nasal permeability of PIO ex-vivo significantly; in-vivo biodistribution study in rats has shown a direct transport of drug from the nose to brain from the IN-NLC
Research Models SHSY5Y cells; Wistar rats
Main Source
Ref. Link