| Effects |
(1) NIR-activated melatonin release and photothermal effect collectively inhibit Aβ nucleation, self-seeding, and propagation and can also disrupt the preformed Aβ fibers examined using in vitro Aβ aggregation and Aβ-misfolding cyclic amplification assays; (2) The DM-NCs display a higher biocompatibility to neuroblastoma cells, suppress the AD-associated generation of intracellular reactive oxygen species, and are devoid of any negative impact on the axonal growth process; |
