Detailed Information for N00261
IPAD-DB ID N00261
Name nanodiamond
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein β-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Effects Reverse the histopathological changes and mitigate the abnormal BACE1 overexpression; suppress neuronal inflammation and oxidative stress
Research Models Wistar rats
Main Source
Ref. Link