Detailed Information for N00279
IPAD-DB ID N00279
Name Phytol-PLGANPs
Category Nano-inhibitors
EC50 -
IC50 -
Inhibition -
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Butyrylcholinesterase (BChE)
Effects Reduce the Aβ25-35 induced ROS level, protect Neuro-2a cells from Aβ25-35 mediated macromolecular damage, prevent ChE induced aggregation of Aβ peptides and its toxicity in Neuro-2a cells, against Aβ25-35 induced proteotoxicity in C. elegans
Research Models In Neuro-2a cells, in C. elegans
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