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Detailed Information for N00280
IPAD-DB ID
N00280
Name
PiB-MZF
Category
Nano-inhibitors
EC
50
IC
50
Inhibition
Toxicity
no cytotoxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein
Aβ
Effects
PiB co-localized with MZF and Ab plaques, as shown on immunohistochemical stains in mouse models of AD
Research Models
SH-SY5Y cells; ICR and APP/PS1 mice
Main Source
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