Detailed Information for N00281
IPAD-DB ID N00281
Name PLGA
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity protect neurons against Aβ-mediated toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ1-42
Effects By interacting with the hydrophobic domain of Aβ1–42, prevents a conformational shift towards β-sheet structure, thus precluding the formation of Aβ aggregates
Research Models Kinetic study; BALB/c mice
Main Source
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