Detailed Information for N00282
IPAD-DB ID N00282
Name PLGA
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity protect neurons against Aβ-mediated toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Tau protein
Effects PLGA-treated Aβ samples can significantly enhance viability of cortical cultured neurons compared to neurons treated with Aβ alone by attenuating phosphorylation of tau protein
Research Models Kinetic study; BALB/c mice
Main Source
Ref. Link