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Detailed Information for N00284
IPAD-DB ID
N00284
Name
PLGA-PEG-B6/Cur
Category
Nano-inhibitors
EC
50
IC
50
Inhibition
Toxicity
low toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein
Aβ
Effects
Improve the spatial learning and memory capability of APP/PS1 mice; reduce hippocampal Aβ production in APP/PS1 mice
Research Models
HT22 cells; APP/PS1 mice
Main Source
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