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Detailed Information for N00288
IPAD-DB ID
N00288
Name
QD-PEG-BTA
Category
Nano-inhibitors
EC
50
IC
50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein
Aβ1-40
Effects
BTA is able to target to the β2 position of the Aβ fibers with high affinity, which enable the final QD to detect amyloid fibril
Research Models
Docking study
Main Source
Ref. Link