Detailed Information for N00290
IPAD-DB ID N00290
Name rHDL/Do
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity effectively reduce the Aβ-induced cytotoxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Aβ1-42
Effects Accelerate the microglial Aβ internalization; ameliorate neurologic damages, decrease amyloid deposition, and rescue memory loss efficiently in AD mice
Research Models HCMEC/D3, BV-2 and SH-SY5Y cells; ICR mice and SD rats
Main Source
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