Detailed Information for N00291
IPAD-DB ID N00291
Name rHDL/Do
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity effectively reduce the Aβ-induced cytotoxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Acetylcholinesterase (AChE)
Effects Inhibit AChE activity, ameliorate neurologic damages, and rescue memory loss efficiently in AD mice
Research Models HCMEC/D3, BV-2 and SH-SY5Y cells; ICR mice and SD rats
Main Source
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