Detailed Information for N00295
IPAD-DB ID N00295
Name S-Au@TPM
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species) inhibit ROS
Metal Chelating
BBB(blood-brain barrier)
Target Protein Aβ
Effects Increase PC12 cell differentiation and cell viability; improve nuclear apoptosis alternation; increase the levels of SOD and GSH-Px in the sera and hypothalami of AD mice; elevate Nrf2/HO1 expression and reduced Keap1 levels in AD mice
Research Models PC12 cells; AD mice
Main Source
Ref. Link