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Detailed Information for N00296
IPAD-DB ID
N00296
Name
SeQDs
Category
Nano-inhibitors
EC
50
IC
50
Inhibition
Toxicity
significantly reduce Aβ-mediated cytotoxicity
ROS(reactive oxygen species)
have strong free-radical scavenging activity
Metal Chelating
BBB(blood-brain barrier)
PASS
Target Protein
Aβ
Effects
Protect cells from oxidative stress induced by different stimuli; inhibit Aβ aggregationimprove the memory impairment of AD mice, and improve their learning and memory ability
Research Models
In SH-SY5Y cells; white Kunming male mice
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