Detailed Information for N00297
IPAD-DB ID N00297
Name SeQDs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity significantly reduce Aβ-mediated cytotoxicity
ROS(reactive oxygen species) have strong free-radical scavenging activity
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Tau protein
Effects Protect cells from oxidative stress induced by different stimuli; reduce tau protein phosphorylation by down-regulating PHF1 and CP13 and further reduce oxidative stress; improve the memory impairment of AD mice, and improve their learning and memory ability
Research Models In SH-SY5Y cells; white Kunming male mice
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