Detailed Information for E00070
IPAD-DB ID E00070
Name Angelica decursiva CH2Cl2 fraction
Category Natural extracts
EC50
IC50 9.51 ± 1.20 μg/mL(PTP1B); 86.08 ± 1.59 μg/mL(α-Glucosidase); 12.66 ± 0.18 μg/mL(RLAR); 13.71 ± 0.84 μg/mL(AChE); 2.35 ± 0.74 μg/mL(BChE); 20.9 ± 0.41 μg/mL(BACE1);
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein β-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Effects
Research Models Sprague–Dawley rats; In vitro
Main Source
Ref. Link