Detailed Information for E00080
IPAD-DB ID E00080
Name Angelica decursiva H2O fraction
Category Natural extracts
EC50
IC50 >200 μg/mL(PTP1B); >200 μg/mL(α-Glucosidase); >200 μg/mL(RLAR); 2.59 ± 0.59 μg/mL(AChE); 11.36 ± 2.49 μg/mL(BChE); 10.13 ± 0.35 μg/mL(BACE1);
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein β-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Effects
Research Models Sprague–Dawley rats; In vitro
Main Source
Ref. Link