Detailed Information for E00081
IPAD-DB ID E00081
Name Angelica decursiva methanol extract
Category Natural extracts
EC50
IC50 46.81 ± 0.10 μg/mL(PTP1B); 140.57 ± 1.03 μg/mL(α-Glucosidase); 88.17 ± 0.37 μg/mL(RLAR); 16.58 ± 0.78 μg/mL(AChE); 15.63 ± 0.69 μg/mL(BChE); 35.56 ± 1.64 μg/mL(BACE1);
Inhibition 79.39 ± 0.29%(α-glucosidase); 98.90 ± 0.29%(PTP1B); 92.49 ± 1.23%(AChE); 89.19 ± 0.19%(BChE);
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein α-glucosidase; protein tyrosine phosphatase 1B (PTP1B)
Effects
Research Models Sprague–Dawley rats; In vitro
Main Source
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