Detailed Information for E00086
IPAD-DB ID E00086
Name Angelica decursiva n-BuOH fraction
Category Natural extracts
EC50
IC50 24.40 ± 1.07 μg/mL(PTP1B); 167.16 ± 1.13 μg/mL(α-Glucosidase); 64.45 ± 1.51 μg/mL(RLAR); 6.01 ± 0.09 μg/mL(AChE); 0.42 ± 0.01 μg/mL(BChE); 9.1 ± 0.46 μg/mL(BACE1);
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein α-glucosidase; protein tyrosine phosphatase 1B (PTP1B)
Effects
Research Models Sprague–Dawley rats; In vitro
Main Source
Ref. Link