Detailed Information for E00105
IPAD-DB ID E00105
Name Angelica gigas methanol extract
Category Natural extracts
EC50
IC50
Inhibition 76.90 ± 1.70%(α-glucosidase); 97.26 ± 0.19%(PTP1B); 74.51 ± 1.96%(AChE); 71.07 ± 1.23%(BChE);
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein β-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Effects
Research Models Sprague–Dawley rats; In vitro
Main Source
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