Detailed Information for E00170
IPAD-DB ID E00170
Name Cassia obtusifolia EtOAc extracts
Category Natural extracts
EC50
IC50 12.7±0.07 µg/mL(AChE); 19.8±0.27 µg/mL(BChE) ; 68.7±0.20 µg/mL(BACE2) ;
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein β-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Effects
Research Models In vitro; Molecular docking
Main Source
Ref. Link