Detailed Information for E00173
IPAD-DB ID E00173
Name Cassia obtusifolia H2O extracts
Category Natural extracts
EC50
IC50 14.5±0.12 µg/mL(AChE); 32.2±0.66 µg/mL(BChE) ; 60.1±0.95 µg/mL(BACE5) ;
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein β-site amyloid precursor protein cleaving enzyme 1 (BACE1)
Effects
Research Models In vitro; Molecular docking
Main Source
Ref. Link