Açaí extract inhibited neurotoxicity following Aβ1–42 exposure in PC12 cells
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein
Aβ1-42
Effects
(1) Açaí extract inhibited Aβ1–42 fibril and aggregate formation in vitro; (2) Açaí extract protected neuronal cells against Aβ1–42-evoked PC12 loss of cell viability but not Aβ25–35 or pro-oxidant exposure; (3) açaí extract inhibited Aβ1–42 fibril and aggregate formation;