| IPAD-DB ID |
E00254 |
| Name |
Rhizophora mucronata Chloroform extracts |
| Category |
Natural extracts |
| EC50 |
|
| IC50 |
117.86 ± 2.61 μg/ml(AChEI); 52.09 ± 0.29 μg/ml(Butyrylcholinesterase); |
| Inhibition |
100 μg/ml:39.39 ± 0.13%(AChEI); 95.98 ± 0.54%(Butyrylcholinesterase); 200 μg/ml:98.78 ± 0.13%(AChEI); 96.93 ± 1.59%(Butyrylcholinesterase); 300 μg/ml:99.09 ± 0.033%(AChEI); 97.04 ± 0.20%(Butyrylcholinesterase); 400 μg/ml:99.8 ± 0.000019%(AChEI); 97.16 ± 0%(Butyrylcholinesterase); 500 μg/ml: 99.88 ± 0.000019%(AChEI); 97.75 ± 0.20%(Butyrylcholinesterase); |
| Toxicity |
|
| ROS(reactive oxygen species) |
|
| Metal Chelating |
|
| BBB(blood-brain barrier) |
|
| Target Protein |
Acetylcholinesterase (AChE) |
| Effects |
(1) DPPH scavenging activity: 74.79 ± 0.01% of inhibition; OH• scavenging activity: 84.76 ± 0.1% of inhibition; NO• scavenging activity: 83.69 ± 0.04% of inhibition; H2O2 scavenging activity: 41.99 ± 0.08% of inhibition; Metal chelating activity: 24.25 ± 0.07% of inhibition; |
| Research Models |
In vitro |
| Main Source |
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| Ref. Link |
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