Detailed Information for E00257
IPAD-DB ID E00257
Name Rhizophora mucronata Dichloromethane extracts
Category Natural extracts
EC50
IC50 57.06 ± 1.20 μg/ml(Butyrylcholinesterase);
Inhibition 100 μg/ml: 88.07 ± 2.88%(Butyrylcholinesterase); 200 μg/ml: 87.13 ± 2.0%(Butyrylcholinesterase); 300 μg/ml: 91.14 ± 0.35%(Butyrylcholinesterase); 400 μg/ml: 95.16 ± 1.13%(Butyrylcholinesterase); 500 μg/ml: 95.75 ± 0.70%(Butyrylcholinesterase);
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Butyrylcholinesterase (BChE)
Effects (1) DPPH scavenging activity: 89.54 ± 0.0% of inhibition; OH• scavenging activity: 60.97 ± 0.03% of inhibition; NO• scavenging activity: 50.63 ± 0.01% of inhibition; H2O2 scavenging activity: 90.84 ± 0.09% of inhibition; Metal chelating activity: 34.03 ± 0.05% of inhibition;
Research Models In vitro
Main Source
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