| IPAD-DB ID |
E00258 |
| Name |
Rhizophora mucronata Ethyl acetate extracts |
| Category |
Natural extracts |
| EC50 |
|
| IC50 |
69.21 ± 1.98 μg/ml(AChEI); 53.48 ± 0.40 μg/ml(Butyrylcholinesterase); |
| Inhibition |
100 μg/ml:72.23 ± 0.95%(AChEI); 93.50 ± 0.20%(Butyrylcholinesterase); 200 μg/ml:78.08 ± 0.47%(AChEI); 93.50 ± 0.20%(Butyrylcholinesterase); 300 μg/ml:78.48 ± 2.44%(AChEI); 94.80 ± 0.89%(Butyrylcholinesterase); 400 μg/ml:79.98 ± 3.74%(AChEI); 96.45 ± 1.97%(Butyrylcholinesterase); 500 μg/ml: 81.12 ± 2.67%(AChEI); 97.52 ± 1.84%(Butyrylcholinesterase); |
| Toxicity |
|
| ROS(reactive oxygen species) |
|
| Metal Chelating |
|
| BBB(blood-brain barrier) |
|
| Target Protein |
Acetylcholinesterase (AChE) |
| Effects |
(1) DPPH scavenging activity: 60.75 ± 0.07% of inhibition; OH• scavenging activity: 83.41 ± 0.02% of inhibition; NO• scavenging activity: 94.86 ± 0.01% of inhibition; H2O2 scavenging activity:95.13 ± 0.04% of inhibition; Metal chelating activity: 9.94 ± 0.03% of inhibition; |
| Research Models |
In vitro |
| Main Source |
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| Ref. Link |
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