| IPAD-DB ID |
E00262 |
| Name |
Rhizophora mucronata Methanol extracts |
| Category |
Natural extracts |
| EC50 |
|
| IC50 |
59.31 ± 0.35 μg/ml(AChEI); 51.72 ± 0.33 μg/ml(Butyrylcholinesterase); |
| Inhibition |
100 μg/ml: 84.30 ± 1.22%(AChEI); 96.66 ± 1.09%(Butyrylcholinesterase); 200 μg/ml: 84.55 ± 0.34%(AChEI); 98.07 ± 0.17%(Butyrylcholinesterase); 300 μg/ml:87.43 ± 1.14%(AChEI); 98.15 ± 0.52%(Butyrylcholinesterase); 400 μg/ml:88.49 ± 0.302%(AChEI); 98.88 ± 0.76%(Butyrylcholinesterase); 500 μg/ml: 92.73 ± 0.54%(AChEI); 98.98 ± 0.17%(Butyrylcholinesterase); |
| Toxicity |
|
| ROS(reactive oxygen species) |
|
| Metal Chelating |
|
| BBB(blood-brain barrier) |
|
| Target Protein |
Acetylcholinesterase (AChE) |
| Effects |
(1) DPPH scavenging activity: 91.05 ± 0.07% of inhibition; OH• scavenging activity: 95.16 ± 0.02% of inhibition; NO• scavenging activity: 89.13 ± 0.06% of inhibition; H2O2 scavenging activity: 96.4 ± 0.04% of inhibition; Metal chelating activity: 90.21 ± 0.02% of inhibition; |
| Research Models |
In vitro |
| Main Source |
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| Ref. Link |
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