Detailed Information for E00266
IPAD-DB ID E00266
Name Rhizophora mucronata Petroleum ether extracts
Category Natural extracts
EC50
IC50 60.21 ± 0.23 μg/ml(Butyrylcholinesterase);
Inhibition 100 μg/ml: 80.99 ± 2.74%(Butyrylcholinesterase); 200 μg/ml: 82.59 ± 2.09%(Butyrylcholinesterase); 300 μg/ml: 90.41 ± 2.82%(Butyrylcholinesterase); 400 μg/ml: 90.64 ± 0.34%(Butyrylcholinesterase); 500 μg/ml: 94.54 ± 0.72%(Butyrylcholinesterase);
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Acetylcholinesterase (AChE)
Effects (1) DPPH scavenging activity: 20.21 ± 0.05% of inhibition; OH• scavenging activity: 90.65 ± 0.07% of inhibition; NO• scavenging activity: 54.21 ± 0.02% of inhibition; H2O2 scavenging activity: 96.47 ± 0.04% of inhibition; Metal chelating activity: 100.0 ± 0.02% of inhibition;
Research Models In vitro
Main Source
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