Detailed Information for E00268
IPAD-DB ID E00268
Name Rhizophora mucronata Water extracts
Category Natural extracts
EC50
IC50 64.58 ± 1.7 μg/ml(Butyrylcholinesterase);
Inhibition 100 μg/ml: 77.49 ± 0.76%(Butyrylcholinesterase); 200 μg/ml: 77.90 ± 8.47%(Butyrylcholinesterase); 300 μg/ml: 79.40 ± 3.02%(Butyrylcholinesterase); 400 μg/ml: 79.71 ± 3.78%(Butyrylcholinesterase); 500 μg/ml: 84.66 ± 1.55%(Butyrylcholinesterase);
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Acetylcholinesterase (AChE)
Effects (1) DPPH scavenging activity: 39.64 ± 0.05% of inhibition; OH• scavenging activity: 60.45 ± 0.09% of inhibition; NO• scavenging activity: 57.95 ± 0.01% of inhibition; H2O2 scavenging activity: 45.30 ± 0.04% of inhibition; Metal chelating activity: 98.02 ± 0.02% of inhibition;
Research Models In vitro
Main Source
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