Detailed Information for E00278
IPAD-DB ID E00278
Name Rumex hastatus crude saponins extract
Category Natural extracts
EC50
IC50 500 μg/mL: 135 μg/mL(AChEI); 165 μg/mL(BChEI); 312 μg/mL(DPPH)
Inhibition 1000 μg/mL: 81.67 ± 0.88%(AChEI); 77.52 ± 3.28%(BChEI); 63.34 ± 0.98%(DPPH); 500 μg/mL: 72.87 ± 1.27%(AChEI); 63.93 ± 0.67%(BChEI); 56.32 ± 1.06%(DPPH); 250 μg/mL: 60.95 ± 2.01%(AChEI); 61.83 ± 1.21%(BChEI);48.05 ± 0.75%(DPPH); 125 μg/mL: 49.08 ± 1.04%(AChEI); 42.22 ± 1.28%(BChEI); 44.70 ± 1.25%(DPPH); 62.5 μg/mL: 38.74 ± 0.68%(DPPH)
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier)
Target Protein Acetylcholinesterase (AChE)
Effects
Research Models In vitro
Main Source
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